Home    | Feature Article  |  E-ahead of Print   |  Archives   | Author Guidline   | Editorial Board

About the Journal of Applied Virology  
 Journal of Applied Virology (J. Appl. Virol. Print ISSN: 2305-5154; Online ISSN: 2306-6210) is an open access, peer- reviewed journal that considers articles on all aspects of virology, including research on viruses of human, animals, plants, bacteria and fungi. The journal also considers articles on biological products, especially for viral vaccine, etc. The journal welcomes research articles as following:
  • Virion structure and assembly,
  • Viral genome replication and regulation of gene expression,
  • Genetic diversity and evolution,
  • Viral pathogenesis and immunity,
  • Viral vaccines and antiviral agents,
  • Virus-cell interactions, cellular responses to infection,
  • Transformation and oncogenesis,
  • Gene delivery and molecular biochemistry,
  • Novel methods on virology and pre-clinical and clinical studies of anti-viral therapies.

 

Crrent Issues    Number 4  Volume 8

Articles @ Virology

Ying Zhao, Huan Yu, Ni Li, GuoHua Huang

 

Abstract


 

Homologues of Heliothis virescens ascovirus 3h (HvAV-3h) orf21 are found in 9 completely sequenced members of the ascoviruses, but so far their functions are unknown. Here, orf21 (3h-21) was cloned in-frame into a pET-28a bacterial expression vector. The fusion protein produced by this construct was used for the preparation of a polyclonal antiserum. RT-PCR analysis showed a single transcript of 3h-21 of approximately 0.7kb was transcribed beginning at 24h post-infection in infected Helicoverpa armigera larvae. Western blot analysis of extracts from HvAv-3h-infected Helicoverpa armigera larvae detected a 25.6 kDa protein late in infection. This antiserum also reacted with a 25.6 kDa protein in purified virions of HvAv-3h. The protein was not extensively modified post-translation. Immunoelectron microscopy confirmed that the 3H-21 is associated with the structure of HvAV-3h virions.


 

Keywords


 
Ascovirus, HvAV-3h, Structural Protein, 3H-21

 

Full Text:

PDF


DOI: 
https://doi.org/10.21092/jav.v8i4.114
 
Jia Li, Leitai Shi, Yunpeng Wang, Shouchun Cao

 

Abstract


 

Objective To analyze the current epidemiological characteristics of rabies in China, grasp the law of epidemic changes, and provide scientific basis for rabies prevention and control strategies in China.

Methods The data of human rabies prevention and control in China were systematically collected, combined with the genetic sequences of rabies virus street virus epidemic strains in various provinces of China, and statistical and molecular biological methods were used for statistics and analysis. 

Results The number of rabies cases and deaths in China has decreased year by year. At present, the main method of human rabies transmission in China is dog injury. Post-exposure treatment showed an increase in the rate of self-treatment, a decline in the overall immunity rate of the vaccine, and an increase in the rate of passive immunity. Human rabies vaccines are currently available to meet vaccination needs. In addition, the immune rates of dogs and cats did not change significantly. The rabies street virus strains in China are mainly divided into 6 species including China -China ♪. 

Conclusion In terms of infrastructure, it is still necessary to increase the number of primary clinics, improve the professional capabilities of medical staff, and strengthen publicity and education on rabies prevention and treatment. In the areas with high incidence of cases, vaccines similar to street strain should be selected for immunization of human and animal.

 

 

Keywords


 
Rabies, Prevention and Control

 

Full Text:

PDF


DOI: 
https://doi.org/10.21092/jav.v8i4.115

 

 

 
 
 
Manuscript Tracking System
   
 

 

Submit Manuscript
  • The author should register as authour firstly by click the follows link.

 

  • Submit your article by login in the Manuscript Tracking System with your username and password.

 

 

Editorial Team

Honorary Chief Editor

Prof. Farhad Imani :ViraSource Laboratories, North Carolina,27709, USA

Chief Editor  

Dr.  Wenbo Zhang:North Carolina State Laboratory Of Public Health, Raleigh, North Carolina, USA

 Dr. Kongxin Hu:Chinese Academy of Inspection and Quarantine, China

Associate Chief Editor  

Dr. Tengchuan Jin: University of Science and Technology of China

Dr.  Tao Wang : School of Life Sciences,Tianjin University , China

Dr.  Fushun Zhang: The University of Texas Health Science Center at San Antonio, Texas, USA

Managing Director  

Dr.  Kai Wang:Institut Pasteur of Shanghai, Chinese Academy of Sciences, China

 

Abstracted/Indexed in
 

Google Scholar
    http://scholar.google.com/

  CrossRef

Index Copernicus

Directory of Open Access Journals (DOAJ)

  
NewJour
CiteFactor:

WorldCat

JournalTOC:

JournalSeek

CAB Abstracts

Baidu Scholar

Publons

JournalGuide

 

All Published work is licensed under a Creative Commons Attribution 4.0 International License
Copyright © 2012-2021 All rights reserved