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Number 4  Volume 7  

Articles @ Virology

Lei He, Huan Yu, Yiyi Ou-Yang, Jing Peng, Shuangqing Liu, Guohua Huang




Polydnaviruses, double-stranded DNA viruses with segmented genomes, have evolved as obligate endosymbionts of parasitoid, and plays a very important role in the life cycle of parasitoids. The PDV symbiotic with different endoparasites are often different. Here we completed the the six protein tyrosine phosphatases (PTPs) and six ankyrins sequence of a PDV which from Microplitis similis, by sequencing and compared the gene features of this PDV to those of other polydnaviruses. Phylogenetic analysis indicated that it was closely related to Microplitis demolitor BV (MdBV) and Microplitis mediator BV (MmBV), and this result was supported by nucleotide multiple sequence alignment. So a new species of PDV-MsBV was identified and characterized in Microplitis similis. It provides a new material for the co-evolution of biology. At the same time, the structure and function of these 12 proteins were predicted and analyzed. The results showed a new perspective on the study of PTPs and ankyrins protein family in PDVs, and provide the materials and foundations for analysizing the function of MsBV.



Microplitis similis; Polydnaviridae; Protein tyrosine phosphatases; Ankyrins

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DOI: https://doi.org/10.21092/jav.v7i4.104


Leitai Shi, Xiaohuan Zhang, Yongxin Yu




Residues of bovine serum albumin in viral vaccines can cause allergic reactions. The quality control of bovine serum is a prerequisite for ensuring the safety and reliability of the vaccine. Domestic and foreign regulatory authorities have made clear limits on bovine serum residues.



Bovine serum; Quality control; viral vaccines


Full Text:  PDF

DOI: https://doi.org/10.21092/jav.v7i4.107


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Editorial Team

Honorary Chief Editor

Prof. Farhad Imani :ViraSource Laboratories, North Carolina,27709, USA

Chief Editor  

Dr.  Wenbo Zhang:North Carolina State Laboratory Of Public Health, Raleigh, North Carolina, USA

 Dr. Kongxin Hu:Chinese Academy of Inspection and Quarantine, China

Associate Chief Editor  

Dr. Tengchuan Jin: University of Science and Technology of China

Dr.  Tao Wang : School of Life Sciences,Tianjin University , China

Dr.  Fushun Zhang: The University of Texas Health Science Center at San Antonio, Texas, USA

Managing Director  

Dr.  Kai Wang:Institut Pasteur of Shanghai, Chinese Academy of Sciences, China


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