A Systematic Review and Analysis of the Mechanism and Clinical Effects of LIAN HUA QING WEN in the Treatment of Sars-cov-2 Infections

Abstract

LIAN HUA QING WEN(LHQW) is derived from two classic formulas of Han Dynasty and Qing Dynasty, namely, Ma Xing Shi Gan Tang and Drinking Qiao San, which is a heat-clearing and detoxifying proprietary Chinese medicine with the efficacy of clearing plague and removing toxins and promoting the lungs to release heat, and is mainly used for the treatment of influenza, which is a syndrome of heat and toxin attacking the lungs, and in the routine treatment of the new coronavirus pneumonia, it is used for the fever, cough and malaise caused by the mild and common types.LHQW consists of 13 components, 61 main compounds , the mechanism of action involves the intervention of immune system processes, cell proliferation, apoptosis and invasion, toxic metabolism, cytokine activity, and regulation of synthetic processes, etc., and has shown good clinical therapeutic efficacy and safety. The research method based on the combination of experiment and histology has greatly promoted the development of traditional Chinese medicine drugs and provided research ideas for the modernisation and internationalisation of Chinese medicine.